{"id":609,"date":"2018-10-25T06:02:36","date_gmt":"2018-10-25T06:02:36","guid":{"rendered":"http:\/\/www.drcocco.org\/?page_id=609"},"modified":"2020-03-18T10:20:19","modified_gmt":"2020-03-18T10:20:19","slug":"biotechnology","status":"publish","type":"page","link":"https:\/\/www.drcocco.org\/en\/biotechnology\/","title":{"rendered":"Biotechnology"},"content":{"rendered":"

World’s only 100% authentic bio-identical recombinant STGF<\/h2>\n

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“Biotechnology means any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use.”<\/h4>\n

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Genetic engineering is an important discipline of biotechnology and has a wide range of applications covering new drug developments, environmental conservation, energy generation and crop improvements yielding plants that could withstand various external insults. Through genetic engineering, a target (recombinant) protein could be produced efficiently using the machinery of the foster host. The engineered host may undergo fermentative cultivation to attain large quantities of the recombinant protein. Subsequent to purification to remove the contaminants, the recombinant protein is attainable as a highly pure, fully bioactive and authentic product.<\/p>\n

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Bacterial Expression Systems<\/h2>\n

1)\u00a0Escherichia coli\u00a0Excretion System<\/p>\n

We have developed unique\u00a0E. coli\u00a0excretion systems using the Tac and LacUV5 cassettes, in conjunction with plasmid stabilizers for efficient production of recombinant proteins.<\/p>\n

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2)\u00a0Bacillus subtilis\u00a0Secretion System<\/p>\n

Another expression & secretion system is engineered in\u00a0B. subtilis\u00a0for efficient extracellular production of heterologous proteins. Regulatory cassettes containing transcriptional controls derived from the\u00a0veg\u00a0I promoter and the Staphylococcal protein A signal peptide are employed in this system.<\/p>\n

There are many advantages of the extracellular approach over the intracellular one for the production of recombinant proteins.<\/p>\n